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Otobone®: Three-dimensional printed Temporal Bone Biomodel for Simulation of Surgical Procedures
(Int Arch Otorhinolaryngol. 2019 Oct;23(4):e451-e454. doi: 10.1055/s-0039-1688924., 2019-10)INTRODUCTION: The anatomy of the temporal bone is complex due to the large number of structures and functions grouped in this small bone space, which do not exist in any other region in the human body. With the difficulty ... -
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Stem-cell therapy for hearing loss: are we there yet?
(Braz J Otorhinolaryngol. 2019 Jul - Aug;85(4):520-529. doi: 10.1016/j.bjorl.2019.04.006., 2019-07)INTRODUCTION: Mammalian hair cells and auditory neurons do not show regenerative capacity. Hence, damage to these cell types is permanent and leads to hearing loss. However, there is no treatment that re-establishes auditory ... -
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Hearing Health: A Major Concern for the 21st Century
(Int Arch Otorhinolaryngol. 2019 Jul;23(3):e254-e255. doi: 10.1055/s-0039-1692980., 2019-07)The results of the most recent studies on Global Burden of Disease (GBD) indicate a growing and, now, alarming burden of hearing loss. Researches involved in hearing loss are being targeted to provide detailed information ... -
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Contribution of the GSTP1 c.313A>G variant to hearing loss risk in patients exposed to platin chemotherapy during childhood.
(Clin Transl Oncol. 2019 May;21(5):630-635. doi: 10.1007/s12094-018-1964-7., 2019-05)BACKGROUND AND AIM: Ototoxicity is a potential adverse effect of chemotherapy with platin drugs, such as cisplatin and carboplatin, in children. Hearing loss (HL) affecting frequencies below 4 kHz can compromise speech ... -
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Evaluation of selective attention in patients with misophonia.
(Braz J Otorhinolaryngol. 2019 May - Jun;85(3):303-309. doi: 10.1016/j.bjorl.2018.02.005., 2019-05)INTRODUCTION: Misophonia is characterized by the aversion to very selective sounds, which evoke a strong emotional reaction. It has been inferred that misophonia, as well as tinnitus, is associated with hyperconnectivity ... -
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Speech Recognition of Cochlear Implant Users Inside a Noisy Helicopter Environment.
(Audiol Neurootol. 2019 Apr 5;24(1):32-37. doi: 10.1159/000497031., 2019-04)In this study, we tested whether the speech recognition, through radio communications, of cochlear implant (CI) users inside a noisy helicopter cockpit is adequate for safe flight. Method: Speech recognition tests (sentences, ... -
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Caloric test and video head impulse test sensitivity as vestibular impairment predictors before cochlear implant surgery.
(Clinics (Sao Paulo). 2019 Mar 14;74:e786. doi: 10.6061/clinics/2019/e786., 2019-03)OBJECTIVES: Currently, cochlear implant procedures are becoming increasingly broad and have greatly expanded. Bilateral cochlear implants and cochlear implants are more frequently applied in children. Our hypothesis is ... -
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Further evidence for loss-of-function mutations in the CEACAM16 gene causing nonsyndromic autosomal recessive hearing loss in humans.
(J Hum Genet. 2019 Mar;64(3):257-260. doi: 10.1038/s10038-018-0546-4., 2019-03)Mutations in the CEACAM6 gene were first described as causing autosomal dominant nonsyndromic hearing loss, but two splice-altering variants have been recently described as causing autosomal recessive nonsyndromic hearing ... -
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Stem Cells from Human Exfoliated Deciduous Teeth (SHED) Differentiate in vivo and Promote Facial Nerve Regeneration.
(Cell Transplant. 2019 Jan;28(1):55-64. Doi: 10.1177/0963689718809090., 2019-01)Post-traumatic lesions with transection of the facial nerve present limited functional outcome even after repair by gold-standard microsurgical techniques. Stem cell engraftment combined with surgical repair has been ... -
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Video head impulse test relevance in the early postoperative period after cochlear implantation.
(Acta Otolaryngol. 2019 Jan;139(1):6-10. Doi: 10.1080/00016489.2018.1535194., 2019-01)BACKGROUND: Cochlear implantation (CI) is the gold standard therapy for profound or severe sensorineural hearing loss. It is a safe surgical procedure but, because of the proximity of the cochlea and vestibule, postoperative ...
