Artigo
Godoy, Maria Dantas Costa Lima; Fornazieri, Marco Aurélio; Doty, Richard L.; Pinna, Fábio de Rezende; Farfel, José Marcelo; Santos, Glaucia Bento dos; Molina, Mariana; Ferretti-Rebustini, Renata E. L.; Leite, Renata E. P.; Suemoto, Claudia K.; Grinberg, Lea T.; Pasqualucci, Carlos A. G.; Voegels, Richard Louis; Nitrini, Ricardo; Jacob Filho, Wilson (Ann Otol Rhinol Laryngol. 2019 Mar;128(3):184-192. doi: 10.1177/0003489418814865., 2019-03)
OBJECTIVES: The clinical symptoms of Alzheimer’s disease (AD) are preceded by a long asymptomatic period associated with “silent” deposition of aberrant paired helical filament (PHF)-tau and amyloid-beta proteins in brain ...